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Sepsis Differential

Pseudosepsis
Hemorrhage    
Pulmonary embolism         
Myocardial infarction      
Immune Reconstitution Syndrome (HIV patients started on HAART)
Diabetic (abdominal crisis) ketoacidosis
SLE flare with abdominal crisis           
Ventricular pseudoaneurysm        
Massive aspiration/atelectasis   
Systemic vasculitis          
Diuretic-induced hypovolemia
Acute pancreatitis
Acute mesenteric ischemia
Anaphylaxis
Spinal cord injury
Adrenal insufficiency/adrenal hemorrhage
Viscosupplementation of joints
Salicylate toxicity
Toxic Shock Syndrome
Macrophage Activating Syndrome
Intrathecal Baclofen withdrawal
Alcohol withdrawal
Temporal Arteritis
Cerebral Hemorrhage
Too many toxidromes to list...

Differential Diagnosis for sepsis sources
GI source
Abscess
Obstruction
Instrumentation
Cholangiitis
Peritonitis
Necrotizing Pancreatitis

Genitourinary tract source
Pyelonephritis
Intra/perinephric abscess
Renal calculi
Urinary tract obstruction
Acute prostatitis/abscess
Renal insufficiency
Instrumentation in patients with bacteriuria

Pelvic source
Urethritis
Cystitis
Cervicitis
Vaginitis
Peritonitis Abscess

Upper respiratory tract source
Pharyngitis
Sinusitis
Bronchitis
Otitis

Lower respiratory tract source
Community-acquired pneumonia
Hospital acquired pneumonia
Empyema
Lung abscess

Intravascular source
Catheter-associated bacteriuria
Infected prosthetic device
Acute bacterial endocarditis

Skin/soft-tissue source
Osteomyelitis
Necrotizing faciitis
Uncomplicated wound infections

Cardiovascular source
Acute bacterial endocarditis
Myocardial/perivalvular ring abscess

Central nervous system source
Bacterial meningitis

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